BDBM50346122 2-(4-(2-(4-bromo-5-methylthiophen-2-yl)-5-ethyl-6-methylpyrimidin-4-ylamino)phenyl)acetic acid::CHEMBL1782307

SMILES CCc1c(C)nc(nc1Nc1ccc(CC(O)=O)cc1)-c1cc(Br)c(C)s1

InChI Key InChIKey=PPZMBSPWXBMUSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346122   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346122(2-(4-(2-(4-bromo-5-methylthiophen-2-yl)-5-ethyl-6-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human PDE4D3 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346122(2-(4-(2-(4-bromo-5-methylthiophen-2-yl)-5-ethyl-6-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed