BDBM50346152 5-(2-(3-chloropropoxy)-4-methoxyphenyl)-3-phenylisoxazole::CHEMBL1783778

SMILES COc1ccc(-c2cc(no2)-c2ccccc2)c(OCCCCl)c1

InChI Key InChIKey=GDVYBLFYHQBVHZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346152   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50346152(5-(2-(3-chloropropoxy)-4-methoxyphenyl)-3-phenylis...)
Affinity DataIC50:  5.68E+4nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50346152(5-(2-(3-chloropropoxy)-4-methoxyphenyl)-3-phenylis...)
Affinity DataIC50:  5.69E+4nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed