BDBM50346209 5-(3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)-N-methylpyrazine-2-carboxamide::CHEMBL1783890
SMILES CNC(=O)c1cnc(Oc2ccc3CCN(CCc3c2)C2CCC2)cn1
InChI Key InChIKey=DGWKVXVCPCPOAK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50346209
Affinity DataKi: 0.200nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.832nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from rat histamine H3 receptor expressed in HEK293 cells after 45 mins by liquid scintillation spectromet...More data for this Ligand-Target Pair
Affinity DataKi: 1.59E+3nMAssay Description:Binding affinity to human histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >3.16E+3nMAssay Description:Binding affinity to human histamine H2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Inverse agonist activity at human histamine H3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair