BDBM50346229 5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3-yl)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]-1-methoxypyridin-2(1H)-one::CHEMBL1784131

SMILES COn1cc(ccc1=O)C1=N[C@@]([C@H](C)N1)(c1ccc(F)cc1)c1ccc(F)nc1

InChI Key InChIKey=ZEYKOXALDHNSKI-ZSEKCTLFSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50346229   

TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50346229(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50346229(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataIC50: >10nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50346229(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataIC50:  15.7nMAssay Description:Antagonist activity at human recombinant NPYY5 receptor expressed in mouse LMtk- cells co-expressing Gqi5 assessed as inhibition of NPY-induced calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed