BDBM50346554 CHEMBL106011
SMILES Fc1ccc(cc1)-n1sc2ncccc2c1=O
InChI Key InChIKey=QMCIVCACYJRAAY-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50346554
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2A(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of recombinant C-terminal FLAG-tagged human GCN5 expressed in a Baculovirus-infected Sf9 cell expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant human CBP catalytic domainMore data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant His-tagged human PCAF catalytic domain expressed in Baculovirus-infected Sf9 cells using histone H3 as substrate after 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 5.35E+3nMAssay Description:Inhibition of N-terminal His-tagged human p300 HAT (1319 to 1710 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-GST-tagged p300 (965 to 1810 residues) expressed in baculovirus infected Sf9 insect cells preincubated...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Albert-Ludwigs-University Of Freiburg
Curated by ChEMBL
Affinity DataIC50: 9.74E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PCAF HAT domain (493 to 657 residues) expressed in Escherichia coli (BL21 D3) using histone H3 ...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2A(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 8.39E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged GCN5 HAT domain (362 to 837 residues) expressed in baculovirus infected Sf9 cells using histon...More data for this Ligand-Target Pair
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of N-terminal GST-tagged human CBP HAT(1319 to 1710 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of N-terminal His-GST--tagged human P300 expressed in Baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair