BDBM50347087 CHEMBL1796273

SMILES CN(C(=O)c1cc2CCOc3cc(NC(C)=O)ccc3-c2s1)c1ccccc1Cl

InChI Key InChIKey=RTUHEKLMDKJAQG-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50347087   

LigandPNGBDBM50347087(CHEMBL1796273)
Affinity DataKi:  1nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50347087(CHEMBL1796273)
Affinity DataKi:  1.80nMAssay Description:Inhibition of recombinant PI3Kalpha assessed as inhibition of PIP3 formation by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50347087(CHEMBL1796273)
Affinity DataKi:  114nMAssay Description:Apparent binding affinity to PI3Kbeta using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed