BDBM50347095 CHEMBL1796760

SMILES CNC(=O)c1ccc(N(C)C(=O)c2cc3CCOc4cc(ccc4-c3s2)C(=O)NC)c(Cl)c1

InChI Key InChIKey=UPTRETUIYCCQBQ-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347095   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50347095(CHEMBL1796760)Copy SMILESCopy InChI

Affinity DataKi:  2.5nMAssay Description:Inhibition of recombinant PI3Kalpha assessed as inhibition of PIP3 formation by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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