BDBM50348226 CHEMBL1800622

SMILES COc1ccc(cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(F)(F)F)C(C)C

InChI Key InChIKey=ZLMDMGVNLQHTAU-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50348226   

TargetCholesteryl ester transfer protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348226(CHEMBL1800622)
Affinity DataIC50: 15.2nMAssay Description:Inhibition of human recombinant CETP-mediated cholesteryl ester transfer activity after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348226(CHEMBL1800622)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein between exogenous [3H]LD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50348226(CHEMBL1800622)
Affinity DataEC50:  2.60E+3nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348226(CHEMBL1800622)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H]cholesteryl oleate or [3H]triolein using exogenous LDL and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50348226(CHEMBL1800622)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [S35]-MK-0499 binding to human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed