BDBM50348741 CHEMBL1801487

SMILES Fc1ccc2c(Cn3c(nc4ccccc34)C3CCC3)cc(=O)[nH]c2c1F

InChI Key InChIKey=XQZAAJNMEPNWTM-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50348741   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50348741(CHEMBL1801487)
Affinity DataEC50:  260nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as inhibition of nitric oxide production after 18 hrs using 2,3-diaminonaphthalene by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50348741(CHEMBL1801487)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of mouse iNOS expressed in HEK293 cells assessed as inhibition of nitric oxide production after 18 hrs using 2,3-diaminonaphthalene by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50348741(CHEMBL1801487)
Affinity DataEC50:  5.90E+3nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as inhibition A23187 induced nitric oxide production incubated for 24 hrs measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50348741(CHEMBL1801487)
Affinity DataEC50:  320nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed