BDBM50349631 CHEMBL1808989

SMILES O=C(Nc1ccc(cc1)C(=O)NCCN1CCCCC1)Nc1ccc(cc1)-c1nc(O[C@H]2CCOC2)nc(n1)N1CCOCC1

InChI Key InChIKey=XTHMHKVQVQAVJS-MHZLTWQESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349631   

LigandPNGBDBM50349631(CHEMBL1808989)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human PI3Kalpha expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50349631(CHEMBL1808989)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50349631(CHEMBL1808989)
Affinity DataIC50:  8nMAssay Description:Inhibition of human PI3Kgamma expressed in SF9 insect cells after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed