BDBM50349866 CHEMBL160296::CHEMBL1813590::UNC10108016::US9156822, 39

SMILES COc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1

InChI Key InChIKey=HVSUPPZVIPTMEM-UHFFFAOYSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349866   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50349866(CHEMBL160296 | CHEMBL1813590 | UNC10108016 | US915...)
Affinity DataEC50:  0.600nMAssay Description:Partial agonist activity at D2L receptor in human HTLA cells assessed as beta arrestin recruitment at 6 uM after 18 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50349866(CHEMBL160296 | CHEMBL1813590 | UNC10108016 | US915...)
Affinity DataEC50:  2.5nMAssay Description:Partial agonist activity at human D2L receptor expressed in HEK293T cells coexpressing Gi subunit assessed as inhibition of isoproterenol-stimulated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50349866(CHEMBL160296 | CHEMBL1813590 | UNC10108016 | US915...)
Affinity DataEC50:  0.5nMpH: 7.4Assay Description:Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...More data for this Ligand-Target Pair
In DepthDetails US Patent