BDBM50350021 CHEMBL1813067
SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)-c1ccc(=O)[nH]n1
InChI Key InChIKey=XUKROCVZGZNGSI-CQSZACIVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 29 hits for monomerid = 50350021
Affinity DataKi: 2nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]NAMH from human cloned 5HT3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]NAMH from human H3R expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Antagonist activity at histamine H3 receptor in rat cortical membraneMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]NAMH from rat H3R expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H]NAMH from rat cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H]-NAMH from rat histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Binding affinity to rat histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Displacement of [3H]NAMH from rat cloned 5HT3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:Inhibition of muscarinic M2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of adrenergic alpha 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of norepinephrine transporter More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of recombinant human dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of recombinant human norepinephrine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Inverse agonist activity at rat histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Inverse agonist activity at human histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cephalon
Curated by ChEMBL
Cephalon
Curated by ChEMBL
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of recombinant human ERG channel expressed in human HEK 293 cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair