BDBM50350381 CHEMBL1813472

SMILES Clc1ccc(cc1Cl)[C@]12CNC[C@H]1CCCC2

InChI Key InChIKey=UIBIRCANCAKLIN-RISCZKNCSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50350381   

TargetCytochrome P450 2C19(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350381(CHEMBL1813472)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350381(CHEMBL1813472)
Affinity DataIC50:  7.93E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350381(CHEMBL1813472)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350381(CHEMBL1813472)
Affinity DataIC50:  3.64E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by high throughput single cell planar patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350381(CHEMBL1813472)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed