BDBM50350421 CHEMBL1813731

SMILES C[C@@H]1CN([C@@H](C)CN1C[C@@]1(O)CC[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC[C@H]23)C1)S(=O)(=O)c1ccccc1C(F)(F)F

InChI Key InChIKey=IYHGEKFCMCXIEF-AIQQMPNKSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50350421   

Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)

Curated by ChEMBL
LigandPNGBDBM50350421(CHEMBL1813731)
Affinity DataIC50:  13nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chuq (Chul)-Research Center

Curated by ChEMBL
LigandPNGBDBM50350421(CHEMBL1813731)
Affinity DataIC50:  6nMAssay Description:Inhibition of 17Beta-HSD3 expressed in intact HEK293 cells assessed as transformation of [14C]-4-androstene-3,17-dione into [14C]-testosterone in pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chuq (Chul)-Research Center

Curated by ChEMBL
LigandPNGBDBM50350421(CHEMBL1813731)
Affinity DataIC50:  85nMAssay Description:Inhibition of 17betaHSD3 (unknown origin) transfected in human LNCAP cells assessed as conversion of [14C]-4-androstene-3,17-dione into [14C]-testost...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chuq (Chul)-Research Center

Curated by ChEMBL
LigandPNGBDBM50350421(CHEMBL1813731)
Affinity DataIC50:  6nMAssay Description:Inhibition of 17betaHSD3 (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chuq (Chul)-Research Center

Curated by ChEMBL
LigandPNGBDBM50350421(CHEMBL1813731)
Affinity DataIC50:  110nMAssay Description:Inhibition of 17-beta-HSD3 (unknown origin) expressed in human LNCaP cells using [14C]-4-androstene-3,17-dione as substrate assessed as reduction of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed