BDBM50351015 CHEMBL1819176
SMILES Clc1ccc2c(NCCCCCCCNc3c4Cc5ccccc5-c4nc4ccccc34)c3CCCCc3nc2c1
InChI Key InChIKey=ASEDWXNMPGNYLM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50351015
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie
Curated by ChEMBL
Institut F£R Molekulare Physiologie
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie
Curated by ChEMBL
Institut F£R Molekulare Physiologie
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BACE1 expressed in baculovirus assessed as inhibition of amyloid beta-42 production after 60 mins by spectrofluorometric assayMore data for this Ligand-Target Pair