BDBM50351091 CHEMBL1819577

SMILES COc1ccccc1[C@@H](O)c1cc(Cl)cc(OC(C)C)c1N(CC(C)(C)C)C(=O)CCC(=O)N1CCC[C@@H](C1)C(O)=O

InChI Key InChIKey=CLELLBMJLWSCHW-URAOTHONSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50351091   

TargetSqualene synthase(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50351091(CHEMBL1819577)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of squalene synthase in Wistar Charles River rat assessed as formation of squalene using [3H]FPP as substrate after 20 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed