BDBM50351295 CHEMBL1818781

SMILES CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccccc3Cl)ccc2C1

InChI Key InChIKey=KTDMCLCTLWFDGI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50351295   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351295(CHEMBL1818781)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]-MCH from human MCHR1 expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351295(CHEMBL1818781)
Affinity DataIC50:  23nMAssay Description:Displacement of [125I]-MCH from rat MCHR1 expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351295(CHEMBL1818781)
Affinity DataIC50:  65nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced GTPgammaS binding after 60 mins by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed