BDBM50351387 CHEMBL1819077
SMILES CCC(CC)Nc1c2CCCc2nc2c(c(C)nn12)-c1ccc(OC)cc1Cl
InChI Key InChIKey=LDIOUQIXNSSOGU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50351387
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]CRF from human corticotropin-releasing factor receptor 1 expressed in CHO-K1 cells after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Antagonist activity at rat corticotropin-releasing factor receptor 1 expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP production ...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]CRF from corticotropin-releasing factor receptor 1 in rat brain membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Antagonist activity at human corticotropin-releasing factor receptor 1 expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP productio...More data for this Ligand-Target Pair