BDBM50352119 CHEMBL1824515::CHEMBL1852393

SMILES Cc1cnccc1C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45

InChI Key InChIKey=COQZBDBMRLFDRK-XGTKUTNFSA-N

Data  6 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50352119   

TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50352119(CHEMBL1824515 | CHEMBL1852393)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in CHO cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50352119(CHEMBL1824515 | CHEMBL1852393)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]Naloxone from mu opioid receptor expressed in CHO cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50352119(CHEMBL1824515 | CHEMBL1852393)
Affinity DataKi:  97nMAssay Description:Displacement of [3H]norBNI from kappa opioid receptor expressed in CHO cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50352119(CHEMBL1824515 | CHEMBL1852393)
Affinity DataKi:  97nMAssay Description:Displacement of [3H]-norBNI from kappa opioid receptor expressed in CHO cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50352119(CHEMBL1824515 | CHEMBL1852393)
Affinity DataKi:  274nMAssay Description:Displacement of [3H]NTI from delta opioid receptor expressed in CHO cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50352119(CHEMBL1824515 | CHEMBL1852393)
Affinity DataKi:  274nMAssay Description:Displacement of [3H]-NTI from delta opioid receptor expressed in CHO cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50352119(CHEMBL1824515 | CHEMBL1852393)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTP-gammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50352119(CHEMBL1824515 | CHEMBL1852393)
Affinity DataEC50:  39nMAssay Description:Agonist activity at delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTP-gammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50352119(CHEMBL1824515 | CHEMBL1852393)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity against mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50352119(CHEMBL1824515 | CHEMBL1852393)
Affinity DataEC50:  26nMAssay Description:Agonist activity at kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTP-gammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed