BDBM50352528 CHEMBL1824872

SMILES CC(C)(C)c1ccc(COc2cc(cnc2N)-c2ccc(cc2)C(=O)N2CCC[C@@H]2CN2CCCC2)cc1

InChI Key InChIKey=XRNCYEAKFAKLOH-MUUNZHRXSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352528   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352528(CHEMBL1824872)
Affinity DataKi:  980nMAssay Description:Binding affinity to human recombinant c-MET assessed as inhibition of autophosphorylation by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352528(CHEMBL1824872)
Affinity DataIC50:  8.53E+3nMAssay Description:Inhibition of human recombinant c-MET kinase expressed in A549 cells assessed as inhibition of HGF-induced autophosphorylation by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed