BDBM50352579 CHEMBL1825150::US8772288, 27

SMILES Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCS(=O)(=O)CC2)c1)C(=O)NC1CC1

InChI Key InChIKey=CAFLYADBHMSVLL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352579   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352579(CHEMBL1825150 | US8772288, 27)
Affinity DataIC50:  6.70nMpH: 7.5 T: 2°CAssay Description:Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352579(CHEMBL1825150 | US8772288, 27)
Affinity DataIC50:  75nMAssay Description:Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352579(CHEMBL1825150 | US8772288, 27)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed