BDBM50352720 CHEMBL1823216::US8835436, Example 140

SMILES Cc1nc(C(=O)NC[C@H](O)CN2CCN(CC2)c2cccc(C)c2C)c(C)n1-c1ccccc1F

InChI Key InChIKey=LACMMHDNOBHVQF-QFIPXVFZSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352720   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352720(CHEMBL1823216 | US8835436, Example 140)
Affinity DataIC50:  10.3nMAssay Description:Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352720(CHEMBL1823216 | US8835436, Example 140)
Affinity DataIC50:  244nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352720(CHEMBL1823216 | US8835436, Example 140)
Affinity DataIC50:  1.03E+3nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed