BDBM50352761 CHEMBL1823361::US9126931, 353

SMILES CC1(C)c2[nH]c3cc(ccc3c2C(=O)c2cc(CCC3CCCC3)c(cc12)N1CCN(CC1)C1COC1)C#N

InChI Key InChIKey=WDSNMJGRLXTGIN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50352761   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50:  20.3nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50:  186nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of KDR activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of KIT activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50352761(CHEMBL1823361 | US9126931, 353)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MET activity by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed