BDBM50352761 CHEMBL1823361::US9126931, 353
SMILES CC1(C)c2[nH]c3cc(ccc3c2C(=O)c2cc(CCC3CCCC3)c(cc12)N1CCN(CC1)C1COC1)C#N
InChI Key InChIKey=WDSNMJGRLXTGIN-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50352761
Affinity DataIC50: 20.3nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Inhibition of ALK activity by TR-FRET assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of KDR activity by TR-FRET assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of KIT activity by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MET activity by TR-FRET assayMore data for this Ligand-Target Pair