BDBM50354432 CHEMBL1836844

SMILES CC1(C)CN(CCN1)C(=O)c1ccc(Nc2nc(cn3c(cnc23)-c2cn[nH]c2)C2CC2)cc1Cl

InChI Key InChIKey=QODQEZHGGGAGFQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50354432   

TargetAurora kinase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354432(CHEMBL1836844)
Affinity DataIC50:  4.59E+3nMAssay Description:Inhibition of AurBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354432(CHEMBL1836844)
Affinity DataIC50:  3nMAssay Description:Inhibition of BRK pretreated for 30 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354432(CHEMBL1836844)
Affinity DataIC50:  476nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354432(CHEMBL1836844)
Affinity DataIC50:  47nMAssay Description:Inhibition of phosphorylated SAM68 in 293 WT-PTK6 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed