BDBM50354643 CHEMBL1834206

SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(Nc2nc3ccc(F)cc3s2)c(F)c1

InChI Key InChIKey=IOQRTGZPCYYQLE-RTBURBONSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354643   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354643(CHEMBL1834206)
Affinity DataIC50:  73nMAssay Description:Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50354643(CHEMBL1834206)
Affinity DataIC50:  73nMAssay Description:Inhibition of DGAT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed