BDBM50355216 CHEMBL1835807

SMILES CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccccc1

InChI Key InChIKey=DPOBPPOQOUIOGG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50355216   

TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355216(CHEMBL1835807)
Affinity DataIC50:  500nMAssay Description:Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355216(CHEMBL1835807)
Affinity DataIC50:  1.42E+3nMAssay Description:Displacement of [1,2,6,7-3H]PG from human PR-LBD after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355216(CHEMBL1835807)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [3H]DHT from human recombinant androgen receptor-LBD expressed in Escherichia coli after 18 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355216(CHEMBL1835807)
Affinity DataIC50:  3.54E+3nMAssay Description:Displacement of [3H]dexamethasone from human GR measured after 18 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355216(CHEMBL1835807)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355216(CHEMBL1835807)
Affinity DataIC50:  500nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355216(CHEMBL1835807)
Affinity DataIC50:  1.42E+3nMAssay Description:Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PR-LBD (675 to 933 residues) expressed in baculovirus-infected insect cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355216(CHEMBL1835807)
Affinity DataIC50:  3.54E+3nMAssay Description:Displacement of [3H]-dexamethasone from human recombinant glucocorticoid receptor after 18 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed