BDBM50355243 CHEMBL1835836

SMILES Cn1c(ccc1-c1ccc2oc(=O)ccc2c1)C#N

InChI Key InChIKey=HUSRKXRZWRJFRQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50355243   

TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355243(CHEMBL1835836)
Affinity DataIC50:  65nMAssay Description:Antagonist activity at human progesterone receptor in T47D cells after 24 hrs by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355243(CHEMBL1835836)
Affinity DataIC50:  123nMAssay Description:Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355243(CHEMBL1835836)
Affinity DataIC50:  1.52E+4nMAssay Description:Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PR-LBD (675 to 933 residues) expressed in baculovirus-infected insect cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ochanomizu University

Curated by ChEMBL
LigandPNGBDBM50355243(CHEMBL1835836)
Affinity DataIC50:  1.52E+4nMAssay Description:Displacement of [1,2,6,7-3H]PG from human PR-LBD after 24 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed