BDBM50355372 CHEMBL482212

SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@]2(O)Cc1ccccc1

InChI Key InChIKey=HMIDDXLVYVRYHN-WJGLBBAVSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50355372   

TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50355372(CHEMBL482212)
Affinity DataKi:  250nMAssay Description:Inhibition of human steroid sulfatase using 4-methylumbelliferyl sulfate substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50355372(CHEMBL482212)
Affinity DataIC50:  325nMAssay Description:Compound was tested for its ability to inhibit the transformation of [C14]-DHEAS to DHEA by steroid sulfatase derived from human embryonal kidney cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50355372(CHEMBL482212)
Affinity DataIC50:  310nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50355372(CHEMBL482212)
Affinity DataIC50:  325nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50355372(CHEMBL482212)
Affinity DataIC50:  220nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50355372(CHEMBL482212)
Affinity DataIC50:  310nMAssay Description:Estrone sulfatase activity against homogenized human JEG-3 cells was determined by measuring the [3H]E1 obtained from [3H]E1SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50355372(CHEMBL482212)
Affinity DataIC50:  230nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed