BDBM50355989 CHEMBL1911193::US8772288, 53

SMILES Cc1nnc([nH]1)-c1ccc(C)c(c1)-c1ccc2c(NC(=O)C22CCCC2)c1

InChI Key InChIKey=BQFCNELWODTDKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355989   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355989(CHEMBL1911193 | US8772288, 53)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355989(CHEMBL1911193 | US8772288, 53)
Affinity DataIC50:  7.5nMpH: 7.5 T: 2°CAssay Description:Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...More data for this Ligand-Target Pair
In DepthDetails US Patent