BDBM50356161 CHEMBL1909931

SMILES CC(C)c1cccc2cc[n+](C)c(Cc3cccc(Cc4[n+](C)ccc5cccc(C(C)C)c45)c3)c12

InChI Key InChIKey=XMROENZSOFWKAA-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50356161   

TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50356161(CHEMBL1909931)
Affinity DataKi:  46nMAssay Description:Displacement of [125I]-apamin from cloned SK3 channel expressed in human HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50356161(CHEMBL1909931)
Affinity DataKi:  90nMAssay Description:Displacement of [125I]-apamin from cloned SK2 channel expressed in human HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 3(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50356161(CHEMBL1909931)
Affinity DataIC50:  2.97E+3nMAssay Description:Inhibition of cloned human SK3 channel expressed in human HEK293 cells by patch clamp assay in the presence of 1 uM intracellular Ca2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Rattus norvegicus (Rat))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50356161(CHEMBL1909931)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of cloned rat SK2 channel expressed in human HEK293 cells by patch clamp assay in the presence of 1 uM intracellular Ca2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed