BDBM50357119 CHEMBL1917417
SMILES Cc1c(Sc2ccccc2)c2cc(C)ccc2n1CC(O)=O
InChI Key InChIKey=PDLCIHCFWCWZDA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50357119
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human CRTh2 receptor expressed in HEK cells assessed as inhibition of PGD2-induced calcium fluxMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human recombinant aldose reductase 1 after 15 mins by spectrophotometry analysisMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 157nMAssay Description:Inhibition of rat aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair