BDBM50357119 CHEMBL1917417

SMILES Cc1c(Sc2ccccc2)c2cc(C)ccc2n1CC(O)=O

InChI Key InChIKey=PDLCIHCFWCWZDA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50357119   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50357119(CHEMBL1917417)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at human CRTh2 receptor expressed in HEK cells assessed as inhibition of PGD2-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50357119(CHEMBL1917417)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of human recombinant aldose reductase 1 after 15 mins by spectrophotometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50357119(CHEMBL1917417)
Affinity DataIC50:  157nMAssay Description:Inhibition of rat aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50357119(CHEMBL1917417)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed