BDBM50357632 CHEMBL1915867

SMILES Cc1ccc2OC[C@@H](COc3cc(C)c(C(=O)Nc4cc(CC(O)=O)ccc4Cl)c(C)c3)c2c1

InChI Key InChIKey=NXTVJLPVVYHNJC-LJQANCHMSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357632   

TargetProstacyclin receptor(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357632(CHEMBL1915867)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357632(CHEMBL1915867)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed