BDBM503577 6-[4-[3-(5-fluoro-4-oxo-3H-quinazolin-2-yl)propanoyl]piperazin-1-yl]pyridine-3-carbonitrile::US11034670, Ex. 17

SMILES Fc1cccc2nc(CCC(=O)N3CCN(CC3)c3ccc(cn3)C#N)[nH]c(=O)c12

InChI Key InChIKey=MZAAUJMUTYAMFB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503577   

TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM503577(6-[4-[3-(5-fluoro-4-oxo-3H-quinazolin-2-yl)propano...)
Affinity DataIC50:  215nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM503577(6-[4-[3-(5-fluoro-4-oxo-3H-quinazolin-2-yl)propano...)
Affinity DataIC50:  8nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent