BDBM50359214 CHEMBL1923309

SMILES CCN1C(=O)c2nc(-c3ccc(cc3)-c3ccccc3)n(Cc3ccc(F)c(F)c3)c2N2CCC(C)(C)N=C12

InChI Key InChIKey=MORJRWNJEYWBLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359214   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359214(CHEMBL1923309)
Affinity DataIC50:  108nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed