BDBM50361140 CHEMBL1933615

SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccccc1

InChI Key InChIKey=SKSYZEHWGCTZPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361140   

TargetLysine-specific demethylase 4E(Homo sapiens (Human))
Max Delbr�Ck Center For Molecular Medicine In The Helmholtz Gemeinschaft (Mdc)

Curated by ChEMBL
LigandPNGBDBM50361140(CHEMBL1933615)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNatural resistance-associated macrophage protein 2(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361140(CHEMBL1933615)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed