BDBM50363152 CHEMBL455469

SMILES [O-][N+](=O)c1cccc(c1)C(=O)\C=C\c1ccc2OCOc2c1

InChI Key InChIKey=MALGARLLWBWYQV-GQCTYLIASA-N

Data  2 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50363152   

TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50363152(CHEMBL455469)
Affinity DataKi:  4.50E+3nMAssay Description:Competitive inhibition of Yersinia enterocolitica recombinant YopH using pNPP as substrate after 10 mins by Line-weaver Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50363152(CHEMBL455469)
Affinity DataKi:  2.90E+4nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis PTP-A using p-nitrophenyl phosphate as substrate measured for 10 mins by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50363152(CHEMBL455469)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of Yersinia enterocolitica recombinant YopH using pNPP as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50363152(CHEMBL455469)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PTP-B using p-nitrophenyl phosphate as substrate measured for 10 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50363152(CHEMBL455469)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTP-A using p-nitrophenyl phosphate as substrate measured for 10 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50363152(CHEMBL455469)
Affinity DataIC50:  1.07E+5nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21 DE3 using p-nitrophenyl phosphate as substrate measured for 10 mins by spectrofluorimetr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed