BDBM503635 US11034671, Example 22::US11168095, Example 22
SMILES O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(cc12)-n1cnc(c1)C1CC1
InChI Key InChIKey=TYMHPGOGCHMDQX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 503635
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical
US Patent
Sichuan Haisco Pharmaceutical
US Patent
Affinity DataKd: <100nMAssay Description:The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical
US Patent
Sichuan Haisco Pharmaceutical
US Patent
Affinity DataIC50: <100nMAssay Description:Table 2: Alternatively, the protein kinase activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Cor...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Sichuan Haisco Pharmaceutical
US Patent
Sichuan Haisco Pharmaceutical
US Patent
Affinity DataIC50: <100nMAssay Description:Table 1: Briefly, 20 μL aliquots of a 1.5× stock of ASK1, STK Substrate 3 and Assay Buffer were distributed in the wells of a white 384 well Opt...More data for this Ligand-Target Pair