BDBM50364321 CHEMBL1949773

SMILES Fc1cc(F)cc(c1)S(=O)(=O)c1ccc2[C@@H]3CCNC[C@@H]3Oc2c1

InChI Key InChIKey=FECXTVAJHWAPLK-RDJZCZTQSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50364321   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50364321(CHEMBL1949773)
Affinity DataKi:  166nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50364321(CHEMBL1949773)
Affinity DataKi:  166nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50364321(CHEMBL1949773)
Affinity DataKi:  2.18E+3nMAssay Description:Displacement of [3H]LSD from rat recombinant 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50364321(CHEMBL1949773)
Affinity DataKi:  2.18E+3nMAssay Description:Displacement of [3H]LSD from rat recombinant 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50364321(CHEMBL1949773)
Affinity DataIC50:  1.36E+3nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in human astrocytoma cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50364321(CHEMBL1949773)
Affinity DataIC50:  1.36E+3nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in human astrocytoma cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed