BDBM503645 US11034671, Example 33::US11168095, Example 183

SMILES Brc1ccc2OCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3

InChI Key InChIKey=JMXXBZQLMRMRIT-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503645   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM503645(US11034671, Example 33 | US11168095, Example 183)
Affinity DataIC50:  5.50E+3nMAssay Description:Table 1: Briefly, 20 μL aliquots of a 1.5× stock of ASK1, STK Substrate 3 and Assay Buffer were distributed in the wells of a white 384 well Opt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM503645(US11034671, Example 33 | US11168095, Example 183)
Affinity DataKd:  750nMAssay Description:The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent