BDBM50365234 CHEMBL1956278::US9238653, Table 5, Compound 47
SMILES Cc1cc(Nc2ccc(cc2)C(F)(F)F)n2nc(nc2n1)C1CC1
InChI Key InChIKey=TZMPAXWVWBRVRY-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50365234
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 140nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair