BDBM50365782 CHEMBL1956561

SMILES C1CN(CCO1)c1ccc(Nc2ncc(-c3cn[nH]c3)n3ccnc23)cc1

InChI Key InChIKey=LRTDHGYWAOVTQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365782   

TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50365782(CHEMBL1956561)
Affinity DataIC50:  2.82E+3nMAssay Description:Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50365782(CHEMBL1956561)
Affinity DataIC50:  829nMAssay Description:Inhibition of MAPKAPK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed