BDBM50366175 CHEMBL1957606
SMILES ONC(=O)[C@@H]1CS(=O)(=O)CN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1
InChI Key InChIKey=LXQUQEBAZBLBEJ-HNNXBMFYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50366175
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of MMP14 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of MMP8 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of MMP12 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair