BDBM50366305 CHEBI:70328::CHEMBL445599
SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6@H](-[#6][C@]12[#6]-[#6@H](-[#6]\[#6]=[#6](\[#6])-[#6])C([#6])([#6])[C@]([#6]\[#6]=[#6](\[#6])-[#6])([#6](=O)-[#6](-[#6](=O)-c3ccc(-[#8])c(-[#8])c3)=[#6]1-[#8])[#6]2=O)-[#6](-[#6])=[#6]
InChI Key InChIKey=QDKLRKZQSOQWJQ-AKAMJVKKSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50366305
TargetProstaglandin E synthase(Homo sapiens (Human))
Abdul Wali Khan University Mardan
Curated by ChEMBL
Abdul Wali Khan University Mardan
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of mPGES1 in human A549 cell microsomal membrane using pGH2 as substrate pretreated for 15 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Second Military Medical University
Curated by ChEMBL
Second Military Medical University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human p300 expressed in Escherichia coli incubated for 15 mins followed by [3H]acetyl-CoA/histone additionMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Second Military Medical University
Curated by ChEMBL
Second Military Medical University
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of full length His6-tagged recombinant p300 (unknown origin) expressed in baculovirus infected Sf21 cells using human histone as substrate...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
European Biomedical Research Institute Of Salerno (Ebris)
Curated by ChEMBL
European Biomedical Research Institute Of Salerno (Ebris)
Curated by ChEMBL
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human topoisomerase 2beta-mediated relaxation of supercoiled pSG483 DNA after 30 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant FLAG epitope-tagged human PCAF expressed in Baculovirus-infected Sf21 cells using histone as substrate after 10 mins in pre...More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Second Military Medical University
Curated by ChEMBL
Second Military Medical University
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant human full-length His6-tagged p300 expressed in baculovirus infected Sf21 insect cells using [3H]acetylCoA as substrate pre...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
European Biomedical Research Institute Of Salerno (Ebris)
Curated by ChEMBL
European Biomedical Research Institute Of Salerno (Ebris)
Curated by ChEMBL
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pSG483 DNA after 30 mins by ethidium bromide staining based agarose gel e...More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Second Military Medical University
Curated by ChEMBL
Second Military Medical University
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant full-length His6-tagged human P300 expressed in Baculovirus-infected Sf21 cells using histone as substrate after 10 mins in...More data for this Ligand-Target Pair