BDBM50366609 CHEMBL4177507

SMILES N[C@@H]([C@H](OCc1ccccc1)C(=O)Nc1ccc-2c(Cc3ccccc-23)c1)C(O)=O

InChI Key InChIKey=RPXRQPZQCZLBCH-VXKWHMMOSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50366609   

TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50366609(CHEMBL4177507)
Affinity DataIC50:  12nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50366609(CHEMBL4177507)
Affinity DataIC50:  79nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50366609(CHEMBL4177507)
Affinity DataIC50:  47nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50366609(CHEMBL4177507)
Affinity DataIC50:  47nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50366609(CHEMBL4177507)
Affinity DataIC50:  12nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50366609(CHEMBL4177507)
Affinity DataIC50:  55nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50366609(CHEMBL4177507)
Affinity DataIC50:  80nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50366609(CHEMBL4177507)
Affinity DataIC50:  55nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed