BDBM50367253 CHEMBL4167357
SMILES ONC(=O)[C@H]1C[C@@H](CC[C@@H]1C(=O)N1CCC(CC1)c1ccccc1)OC(=O)N1CCCC1
InChI Key InChIKey=ZQQITVPPJYESAU-HKBOAZHASA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50367253
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
University Of Notre Dame
Curated by ChEMBL
University Of Notre Dame
Curated by ChEMBL
Affinity DataKi: 73nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged ADAM10 (Thr214 to Glu672 residues) expressed in baculovirus infected Sf21 cells using McaKPLG...More data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Inhibition of recombinant human MMP12 catalytic domain using Mca-PLGL-DpaAR-NH2 as substrate by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
University Of Notre Dame
Curated by ChEMBL
University Of Notre Dame
Curated by ChEMBL
Affinity DataKi: 900nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ADAM17 (Arg215 to Asn671 residues) expressed in baculovirus infected Sf21 cells using Mca-PLAQ...More data for this Ligand-Target Pair
Affinity DataKi: 8.70E+3nMAssay Description:Inhibition of recombinant human MMP8 catalytic domain (Phe99 to Gln269 residues) expressed in Escherichia coli using McaKPLGL-Dpa-AR-NH2 as substrate...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of APMA activated recombinant human full length MMP2 expressed in mouse cells using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as substra...More data for this Ligand-Target Pair