BDBM50367624 CHEMBL1907841
SMILES CN1c2ccccc2C(=N[C@H](NC(=O)c2ccc(cc2)C(F)(F)F)C1=O)c1ccccc1F
InChI Key InChIKey=XKDCRXFJHGOCJK-OAQYLSRUSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50367624
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 11.0nMAssay Description:Binding affinity against cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair