BDBM50368866 CHEMBL4159656

SMILES C[C@@H](COc1ccc(cc1)[C@H]1Oc2ccc(O)cc2C(C)=C1c1cccc(O)c1)N1CC[C@@H](C)C1

InChI Key InChIKey=JPFFAEPFVTWVBI-QMQXECRNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50368866   

TargetEstrogen receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50368866(CHEMBL4159656)
Affinity DataIC50:  136nMAssay Description:Binding affinity to ERalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50368866(CHEMBL4159656)
Affinity DataIC50:  9.70nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ERalpha protein level after 4 hrs by InCell Western assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50368866(CHEMBL4159656)
Affinity DataIC50:  9.70nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed