BDBM50369720 CHEMBL3979355

SMILES [H][C@@]1(CCCN(C1)C(=O)C(=C\C(C)(C)N1CCN(CC1)C1COC1)\C#N)n1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc12

InChI Key InChIKey=LCFFREMLXLZNHE-GRBCXPRBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50369720   

TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Shaanxi University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50369720(CHEMBL3979355)
Affinity DataIC50:  11nMAssay Description:Inhibition of ErbB4/HER4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma, A Sanofi

Curated by ChEMBL
LigandPNGBDBM50369720(CHEMBL3979355)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of BTK (unknown origin) using peptide substrate in presence of ATP by caliper electrophoresis methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma, A Sanofi

Curated by ChEMBL
LigandPNGBDBM50369720(CHEMBL3979355)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50369720(CHEMBL3979355)
Affinity DataIC50: >5nMAssay Description:Inhibition of JAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed