BDBM50370572 CHEMBL85606::SB-277011

SMILES O=C(N[C@H]1CC[C@H](CCN2CCc3cc(ccc3C2)C#N)CC1)c1ccnc2ccccc12

InChI Key InChIKey=OLWRVVHPJFLNPW-LSNLESRRSA-N

Data  26 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50370572   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50370572(CHEMBL85606 | SB-277011)
Affinity DataKi:  10.7nMAssay Description:Inhibition of [125I]-iodosulpiride binding to rat Dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50370572(CHEMBL85606 | SB-277011)
Affinity DataKi:  11.2nMAssay Description:Inhibition of [125I]iodosulpiride binding to human Dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50370572(CHEMBL85606 | SB-277011)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibition of [125I]iodosulpiride binding to human Dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50370572(CHEMBL85606 | SB-277011)
Affinity DataKi:  2.82E+3nMAssay Description:Inhibition of [125I]iodosulpiride binding to rat Dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed