BDBM50371611 CHEMBL258819

SMILES Oc1c(O)c(cc(C(=O)c2ccc(Oc3ccccc3)cc2)c1O)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=CYBLECRKSFPWGB-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50371611   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50371611(CHEMBL258819)
Affinity DataKi:  37nMAssay Description:Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50371611(CHEMBL258819)
Affinity DataKi:  37nMAssay Description:Inhibition of human Mcl-1 protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50371611(CHEMBL258819)
Affinity DataKi:  1.11E+3nMAssay Description:Binding affinity to human Bcl-xL protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50371611(CHEMBL258819)
Affinity DataIC50:  310nMAssay Description:Inhibition of human Mcl-1 protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50371611(CHEMBL258819)
Affinity DataIC50:  170nMAssay Description:Inhibition of human Bcl-2 protein by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed